Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats
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Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.
PURPOSE To examine the neuroprotective effect of the alpha(2)-adrenergic agonist brimonidine in a chronic ocular hypertension model. METHODS Intraocular pressure (IOP) was elevated by laser photocoagulation of episcleral and limbal veins. Retinal ganglion cell loss was evaluated in wholemounted retinas. Brimonidine or timolol was administered, either at the time of or 10 days after IOP elevat...
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ژورنال
عنوان ژورنال: Experimental Eye Research
سال: 2011
ISSN: 0014-4835
DOI: 10.1016/j.exer.2011.05.008